Jonathan Dench

The paper introduces rSHAPE, a simulation tool for evolutionary experiments, and shows that serial passaging under logistic growth affects mutant fixation probability.

The paper identifies that both epistasis and physical linkage can drive correlated evolution detected computationally under antibiotic selection in Pseudomonas aeruginosa.

This paper evaluates machine learning algorithms for identifying genetic determinants in small sample size, large proteome datasets, showing improved performance with a modified random forest approach.