Author

David Jacob Hermel

University of VermontORCID 0000-0001-6342-6023Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander D. KarabacheviD· 1 shared Dana Solcz· 1 shared Dylan J. MartiniiD· 1 shared Indra Neil SarkariD· 1 shared Marc S. GreenblattiD· 1 shared Marcy E. RichardsoniD· 1 shared Tina F. PesaraniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Alexander D. KarabachevORCID

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1 paper

Recent·Most cited

GeneticsPLoS ONEPeer-reviewedAug 4, 2020

Curated Multiple Sequence Alignment for the Adenomatous Polyposis Coli (APC) Gene and Accuracy of In Silico Pathogenicity Predictions

Alexander D. Karabachev, Dylan J. Martini, David Jacob Hermel…·Marc S. Greenblatt

The paper evaluates how PMSA-based computational tools predict pathogenicity of APC missense variants, finding wide variation in predictions and highlighting challenges in alignment-based methods.

3 citations

humanprotein sequence

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