Evolutionary BiologyNature Machine IntelligencePeer-reviewed
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A generalizable deep learning framework for inferring fine-scale germline mutation rate maps
Yiyuan Fang, Shuyi Deng, Cai Li
MuRaL, a two-module neural network using only DNA sequence, estimates nucleotide-level germline substitution rates, outperforming k-mer and feature-based human models at fine regional scales.
17 citations