BioinformaticsbioRxivPreprint
Deep Mediation Analysis for Multimodal Genotype-Imaging Associations with Disease Phenotypes
Vahid Golderzahi, Guanjie Wang, Jiyuan Hu, Chen‐Hsiang Yeang
The paper introduces GIF, a framework to disentangle direct and indirect genotype-phenotype associations using imaging data, showing image features mediate most associations in ADNI data.
DOI 10.64898/2025.11.20.689376