Sandrine Sarrazin

This study shows that inducing stemness in human macrophages prevents IFNγ-induced exhaustion, enhancing their antitumour activity and persistence in vivo.

The paper identifies Epromoters as cis-regulatory elements that regulate clusters of stress-response genes by recruiting key transcription factors, showing their role across different stress models.

The paper identifies MAFB's role in podocyte differentiation by enabling WT1 binding to specific promoters through chromatin accessibility.