Systems BiologybioRxivPreprint
A mathematical investigation of the interplay between vasculature and intratumoral cellular heterogeneity during tumor progression
Supriya Ghosh, Gopinath Sadhu, D. C. Dalal
This paper develops a mathematical model to study how tumor vasculature and cellular heterogeneity interact during progression, showing angiogenesis increases growth rate and hypoxic cells strongly influence phenotypic switching.
DOI 10.64898/2026.08.26.747242