Author

Richard R. Chapleau

ORCID 0000-0001-6610-5946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Research Focus:polygenic risk· 1

Activity by Year

2022-2023 · peak 2/yr

3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 18, 2023

Genome-wide association study of John Henryism in the CARDIA Cohort suggests a molecular mechanism behind lower nicotine addiction rates

Richard R. Chapleau

The paper conducts a GWAS on John Henryism in the CARDIA Cohort, identifying genetic associations and a molecular pathway linking JH to reduced nicotine addiction.

DOI 10.1101/2023.05.18.23289991

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintMay 16, 2023

Toward Understanding Genetic Risk of Burnout through Genome-wide Associations of Cynicism and Cynical Distrust

Richard R. Chapleau

The paper conducts a GWAS on cynicism and cynical distrust traits using the CARDIA Cohort, identifying genetic variants and pathways linked to health outcomes like cardiovascular disease and addiction.

1 citation

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintDec 12, 2022

Genome-wide Associations, Polygenic Risk, and Mendelian Randomization Reveal Limited Interactions between John Henryism and Cynicism

Richard R. Chapleau

The paper investigates genetic interactions between John Henryism and cynicism using GWAS and machine learning, finding no evidence of interaction despite significant genetic components.

2 citations

humanGWAS summary statistics

𝕏 PostBluesky