Dongfang Zou

The paper identifies three causative genes for childhood epileptic encephalopathies through trio-based whole-exome sequencing and individualized analysis of genetic variants.

This study identifies ZFHX3 variants as a cause of childhood partial epilepsy and infantile spasms, with favorable treatment outcomes and insights into the developmental expression pattern of the gene.

This study evaluates genome sequencing in 320 Chinese children with epilepsy, finding pathogenic variants in 38.13% and demonstrating its diagnostic and therapeutic value.