Temporal Insights into Molecular and Cellular Responses during rAAV Production in HEK293T Cells.
Alok Tanala Patra, Evan Tan, Yee Jiun Kok, Say Kong Ng, Xuezhi Bi
This study identifies host cell proteome changes in HEK293T cells during rAAV production under different transfection conditions, showing a 50% increase in rAAV titre with optimal conditions.
Molecular Therapy — Methods & Clinical Development · Jun 8, 2024Peer-reviewedMolecular Biology