Gene2role: a role-based gene embedding method for comparative analysis of signed gene regulatory networks
Xin Zeng, Shu Liu, Bowen Liu, Weihang Zhang, Kang Xu, Fujio Toriumi, Kenta Nakai
Gene2role embeds genes using multi-hop topological information from signed GRNs to identify topological changes across cell types and quantify module stability.
BMC Bioinformatics · May 24, 2025Peer-reviewedBioinformatics