Author

Francesca Lugli

University of BolognaORCID 0000-0001-6908-5469Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alessio BartocciiD· 1 shared Anna Maria GhelliiD· 1 shared Francesco MusianiiD· 1 shared Francesco ZerbettoiD· 1 shared Jacopo FadanniiD· 1 shared Laura RigobelloiD· 1 shared Leonardo CaporaliiD· 1 shared Luisa IommariniiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Alessio BartocciORCID

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1 paper

Recent·Most cited

BiophysicsInternational Journal of Biological MacromoleculesPeer-reviewedJun 12, 2024

A computational study to assess the pathogenicity of single or combinations of missense variants on respiratory Complex I

Laura Rigobello, Francesca Lugli, Leonardo Caporali…·Francesco Musiani

This study uses molecular dynamics simulations to assess how single or combined missense variants in respiratory complex I affect its function, finding that some variants stiffen key regions and worsen dysfunction.

6 citations

humanstructural biology

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