Author

Rachayata Dharmat

Baylor College of MedicineORCID 0000-0001-6969-4459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Rui CheniD· 2 shared Sangbae KimiD· 2 shared Yumei LiiD· 2 shared Akbar Shakoor· 1 shared Albert T. VitaleiD· 1 shared Denise J. Morgan· 1 shared Hehe LiuiD· 1 shared Ivana K. KimiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Rui ChenORCID

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2 papers

Recent·Most cited

Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling.

Qingnan Liang, Rachayata Dharmat, Leah A. Owen, Akbar Shakoor, Yumei Li, Sangbae Kim, Albert T. Vitale, Ivana K. Kim, Denise J. Morgan, Shaoheng Liang, Nathaniel Wu, Ken Chen, Margaret M. DeAngelis, Rui Chen

This study uses single-nuclei RNA-seq to profile human retinal tissue, identifying cell-type-specific gene expression and improving disease gene prioritization compared to bulk RNA-seq and mouse models.

Nature Communications · Dec 17, 2019Peer-reviewedGenomics

Epigenetic adaptation prolongs photoreceptor survival during retinal degeneration

Rachayata Dharmat, Sangbae Kim, Hehe Liu, Shangyi Fu, Yumei Li, Rui Chen

The paper shows that epigenetic changes allow some photoreceptor cells to survive longer during retinal degeneration in Spata7 mutant mice.

bioRxiv · Sep 18, 2019 · PreprintNeuroscience