Cancer BiologyCancer MedicinePeer-reviewed
Spatial transcriptomics unveils landscape of resistance to concurrent chemo-radiotherapy in hypopharyngeal squamous cell carcinoma: the role of SPP1+ macrophages
Jungyoon Ohn, Sungwoo Bae, Hongyoon Choi…·Kwon Joong Na
This study uses spatial transcriptomics to identify SPP1+ macrophages as key contributors to CCRT resistance in hypopharyngeal SCC by modulating the tumor microenvironment.