Youhe Gao

This study tracks lifetime development in rats using urinary proteome data across 10 timepoints, revealing novel biological pathways involved in development and aging.

The paper identifies 45 differential urine proteins in a CUMS mouse model of MDD, with 24 linked to MDD mechanisms and 10 as potential biomarkers, showing significant non-random changes.

The paper identifies 9 urinary proteins differentially expressed in a TNBS-induced colitis rat model, with 3 previously linked to IBD and 6 newly discovered.

This study identifies differentially expressed urine proteins in two ovarian cancer rat models, suggesting their potential for early detection and monitoring of ovarian cancer progression.

This study profiles lysine-acetylated proteins in normal human urine using immunoaffinity enrichment and mass spectrometry, identifying 629 acetylation sites on 315 proteins.

This study identifies early urinary protein changes that differentiate tumor-forming from non-tumor-forming rats in a lung metastasis model.

The paper describes a device for collecting exhaled breath from small animals to study biomarkers in a rat model of pulmonary emphysema.

The paper investigates whether unilateral relapse of Behcet’s disease uveitis causes asymmetric tear protein profiles, finding no significant differences.

This study identifies differential urinary proteins in a rat model of smoking-induced COPD at different time points, suggesting potential early diagnostic biomarkers.

The paper identifies urinary proteins as early biomarkers for liver fibrosis in a rat model using proteomics and validates their significance before serum enzyme changes and histological fibrosis.

This study identifies early urinary biomarkers for detecting lung metastasis in a Walker-256 rat model using proteomic analysis.

The paper identifies urinary biomarkers in a rat model of autoimmune myocarditis using mass spectrometry and validates some with western blot.

This paper introduces a method to collect and preserve urinary proteins using a fluff pulp diaper, enabling reliable sample collection from infants and special needs patients.

The paper identifies urine biomarkers in glioma patients by comparing pre- and post-tumor resection samples using LC-MS/MS, finding 27 proteins significantly changed.

The paper compares urinary proteomes across three Chinese regions and identifies 62 differentially expressed proteins, highlighting regional differences as a confounding factor in biomarker studies.

This study shows that urine glucose levels become disordered before blood glucose rises in ZDF rats, suggesting urine glucose could be an early diagnostic marker for diabetes.

This study examines how prednisone affects the rat urine proteome and identifies proteins that may serve as disease biomarkers.

This study identifies early urinary biomarkers in a rat cancer model using proteomic analysis, finding 10 proteins that change before tumor palpability and remain significant later.