Regulation of RNA methylation by therapy treatment, promotes tumor survival
Syed I. A. Bukhari, Samuel Spencer Truesdell, Chandreyee Datta, Pritha Choudhury, Keith Q. Wu, Jitendra Shrestha, Ruby Maharjan, Ethan Plotsker, Ramzi K. Elased, Sadia Laisa, Vijeta Bhambhani, Yue Lin, Johannes Kreuzer, Robert Tyler Morris, Siang‐Boon Koh, , Shobha Vasudevan
The paper shows that therapy-induced stress increases METTL3 translation, altering gene expression to promote tumor survival.
bioRxiv · May 19, 2023 · PreprintMolecular Biology