Johannes Kreuzer

This study uses phosphoproteomics to analyze protein phosphorylation during Xenopus oocyte meiotic divisions, revealing key phosphorylation events and their roles in meiotic processes.

This study identifies CDKN1B as a regulator of drug-tolerant persister CTCs by preventing polyploidy after mitotic inhibitor treatment in breast cancer.

This study creates a biliary tract cancer cell line atlas using multi-omics data to identify molecular subtypes and therapeutic targets.

This paper shows that APOE2 gene therapy reduces amyloid deposition, neurodegeneration, and microglial activation in an Alzheimer's mouse model with ongoing APOE4 expression.

The paper shows that therapy-induced stress increases METTL3 translation, altering gene expression to promote tumor survival.

The paper identifies LTR5_Hs viral proteins and virus-like particles in hPGCLCs, showing their activation during early germ cell development and suppression upon gonadal anlagen settlement.

The paper uses multiplexed proteomics to identify synaptic factors linked to cognitive resilience in Alzheimer's Disease by analyzing brain tissue from individuals with varying pathology and cognitive outcomes.