Structural and functional heterogeneity in cardiac RyR signalling nanodomains revealed with quantitative single molecule mapping toolkit
Ralf Köhler, Miriam E. Hurley, Edward White, Izzy Jayasinghe
The paper develops a toolkit to map RyR2 and JPH2 nanodomains in cardiac cells, revealing spatial heterogeneity in their organization and function in right ventricular failure.
bioRxiv · Jul 23, 2026 · PreprintCell Biology