Author

Izzy Jayasinghe

UNSW SydneyORCID 0000-0003-2461-478XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:rat· 1

Frequent Co-Authors

Ralf KöhleriD· 2 shared Barbara CianiiD· 1 shared Daniel A. BoseiD· 1 shared Edward WhiteiD· 1 shared Miriam E. HurleyiD· 1 shared Neftali Flores RodrigueziD· 1 shared Nkolika AtuanyaiD· 1 shared Philip G. WoodmaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Ralf KöhlerORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 23, 2026

Structural and functional heterogeneity in cardiac RyR signalling nanodomains revealed with quantitative single molecule mapping toolkit

Ralf Köhler, Miriam E. Hurley, Edward White, Izzy Jayasinghe

The paper develops a toolkit to map RyR2 and JPH2 nanodomains in cardiac cells, revealing spatial heterogeneity in their organization and function in right ventricular failure.

DOI 10.64898/2026.07.22.740006

ratspatial transcriptomics

𝕏 PostBluesky

BiophysicsbioRxivPreprintOct 1, 2025

Mapping EGFR1 sorting domains in endosomes with a calibrated 3D expansion microscopy toolkit

Tayla Shakespeare, Rajpinder S. Seehra, Neftali Flores Rodriguez…·Izzy Jayasinghe

This paper develops a 3D expansion microscopy toolkit to visualize and quantify nanoscale interactions in endosomes, revealing EGF and EGFR1 enrichment and Rab5a accumulation during endosomal maturation.

3 citations

humanfluorescence / live-cell microscopy

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