Dynamic proteome profiling uncovers age-related impairments in proteostasis and the protective effects of resistance exercise in human skeletal muscle
Yusuke Nishimura, Klaus D. Rudolf, Jennifer S. Barrett…·Jatin G. Burniston
This study uses dynamic proteome profiling to show that resistance exercise improves proteostasis in older human skeletal muscle by increasing mitochondrial protein turnover and restoring proteomic imbalances.