GenomicsDrug Discovery TodayPeer-reviewed
Pathway analysis of GWAS loci identifies novel drug targets and repurposing opportunities
Deepali Jhamb, Michal Magid-Slav, Mark R. Hurle, Pankaj Agarwal
This study uses pathway analysis of GWAS loci to identify novel drug targets and repurposing opportunities for 182 diseases, finding that 30% of diseases have significantly more targets in these pathways than expected by chance.