Chloé Beate Steen

The paper maps the tumor microenvironment in DLBCL using imaging mass cytometry and finds that immune-cell depleted tumors have reduced MHC-I expression and worse survival.

The paper uses scRNA-seq and explainable machine learning to analyze how tumor microenvironment cell types affect neoadjuvant chemotherapy outcomes in breast cancer.

CytoSPACE aligns single-cell and spatial transcriptomes using convex linear optimization, outperforming existing methods in noise-tolerance, accuracy, and efficiency.