BioinformaticsbioRxivPreprint
SurfDiff: protein surface profiling for selective or broadly reactive epitope prioritisation in binder and immunogen design
Benedikt Jedlitzke, Oliver Wissett, Tung H. Nguyen…·Pietro Sormanni
SurfDiff predicts epitope selectivity and cross-reactivity by analyzing protein surface features, outperforming existing metrics in binder and immunogen design.
DOI 10.64898/2025.12.23.696170