Author

Lewis Charles Murtaugh

University of UtahORCID 0000-0001-7353-4706Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:zebrafish· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jonathan M. DownieiD· 2 shared Karla Patricia FigueroaiD· 2 shared Kristi L. Russell· 2 shared Lynn B. JordeiD· 2 shared Mark B. BrombergiD· 2 shared Stefan M. PulstiD· 2 shared Summer B. Gibson· 2 shared Cody J. SteelyiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenetics

Jonathan M. DownieORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 24, 2022

A microbiota membrane disrupter disseminates to the pancreas and increases β-cell mass

Jennifer Hampton Hill, Michelle Sconce Massaquoi, Emily Goers Sweeney…·Karen J. Guillemin

This study identifies BefA, a microbiome-derived protein that promotes β-cell mass by permeabilizing membranes, linking microbiome composition to diabetes risk.

DOI 10.1101/2022.03.24.485696

zebrafishmouse

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 30, 2021

MFN2 Influences Amyotrophic Lateral Sclerosis Pathology

Kristi L. Russell, Jonathan M. Downie, Summer B. Gibson…·Stefan M. Pulst

The paper identifies MFN2 mutations in ALS patients and shows they impair mitochondrial function and increase TDP-43 levels in zebrafish models.

1 citation

humanzebrafish

𝕏 PostBluesky

GeneticsbioRxivPreprintFeb 11, 2019

Loss of TP73 function contributes to amyotrophic lateral sclerosis pathogenesis

Jonathan M. Downie, Summer B. Gibson, Spyridoula Tsetsou…·Lynn B. Jorde

The paper identifies TP73 variants as risk factors for ALS through exome sequencing and functional assays in cell lines and zebrafish.

DOI 10.1101/451419

humanzebrafish

𝕏 PostBluesky