Author

Ebru Çetin

Sabancı ÜniversitesiORCID 0000-0001-7355-8345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Ali Rana AtılganiD· 2 shared Canan AtılganiD· 2 shared Busra TayhaniD· 1 shared Haleh AbdizadehiD· 1 shared Tandac Furkan GucluiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Ali Rana AtılganORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A thermodynamic cycle to predict the competitive inhibition outcomes of an evolving enzyme

Ebru Çetin, Haleh Abdizadeh, Ali Rana Atılgan, Canan Atılgan

This study uses thermodynamic cycles and FEP simulations to predict the effects of resistance mutations on DHFR's competitive inhibition with TMP, revealing structural and dynamical impacts on enzyme function.

Journal of Chemical Theory and Computation · Apr 23, 2025Peer-reviewedBiophysics

High throughput mutational scanning of a protein via alchemistry on a high-performance computing resource

Tandac Furkan Guclu, Busra Tayhan, Ebru Çetin, Ali Rana Atılgan, Canan Atılgan

The paper demonstrates the feasibility of high-throughput mutational scanning of a protein using alchemical free energy calculations on a high-performance computing resource.

Concurrency and Computation Practice and Experience · Jan 16, 2025Peer-reviewedBiophysics