Author

Prathik A. Chakravarthy

The Ohio State University Wexner Medical CenterORCID 0000-0001-7446-7488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexander James DidieriD· 1 shared Alexis MossingiD· 1 shared Beyer Sasha· 1 shared Dillon S. Richardson· 1 shared Gina M. SizemoreiD· 1 shared James W Carpenter· 1 shared Jesse J. ReardoniD· 1 shared Jessica O. WinteriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander James DidierORCID

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1 paper

Recent·Most cited

Breast Cancer-derived PDGFB Remodels the CNS Vascular Niche to Promote Brain, Spinal and Leptomeningeal Metastasis

Nathaniel S Grabinski, Jesse J. Reardon, Sajita Shah, Jonathan J. Adorno, Paul Lee, Rebecca Packard, Yalini Ramamoorthy, Katie Thies, Prathik A. Chakravarthy, Shashwat Agarwal, Jonathan M. Spehar, Tasneem A. Arsiwala, James W Carpenter, Alexis Mossing, Johnathon G. Schiebel, , Gina M. Sizemore

This study shows that breast cancer-derived PDGFB remodels the CNS vascular niche, promoting brain, spinal, and leptomeningeal metastasis through multiple mechanisms.

bioRxiv · Oct 16, 2026 · PreprintCancer Biology