BioinformaticsPLoS ONEPeer-reviewed
Unveiling functional motions based on point mutations in biased signaling systems: A normal mode study on Nerve Growth Factor bound to TrkA
Pedro T. Resende-Lara, David Pérahia, Ana Lígia Scott, Antônio Sérgio Kimus Braz
The paper identifies structural motions affected by a point mutation in the NGF/TrkA-Ig2 complex, showing how these changes impact TrkA activation and nociceptive signaling.
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