Olga Ciccarelli

The paper applies multivariate mechanistic models to a clinical trial in multiple sclerosis to investigate pathways linking simvastatin to clinical outcomes.

This study finds that multiple sclerosis accelerates brain ageing, with older-appearing brains linked to faster disability progression.

This study identifies the sequence of grey matter atrophy progression in multiple sclerosis using longitudinal MRI data and shows its association with disability accumulation in relapsing-remitting MS.

This study shows that deep grey matter volume loss predicts faster disability progression in multiple sclerosis, with specific patterns in different disease subtypes.