Structural insights into a conserved mechanism of choline translocation through CHT
Jesus Vilchez-Garcia, Adrián Martínez-Jiménez, Hanxing Jiang, Miguel Luengo, Borja Ochoa-Lizarralde, Jorge Pedro López-Alonso, Jerónimo Pérez-Lorente, Paola Bartoccioni, Raúl Estévez, Vı́ctor Guallar, Ekaitz Errasti‐Murugarren, Iban Ubarretxena‐Belandia, Igor Tascón
This study identifies a bacterial choline transporter with a structure and mechanism similar to the human CHT1 transporter, revealing conserved choline translocation pathways.
Science Advances · May 29, 2026Peer-reviewedBiophysics