Lu Xie

This study analyzes the intratumoral microbiome in DFSP using WGS data and finds negative correlations between microbial diversity and tumor malignancy markers like Ki67 expression.

ProGeo-neo integrates genomic and proteomic data to improve neoantigen prediction by incorporating mass spectrometry validation and MHC binding prediction.

The paper introduces INeo-Epp, a method for predicting T-cell HLA class-I immunogenic epitopes and neoantigens using sequence-related amino acid features, achieving AUC scores of 0.81 and 0.78.