An open CAR-T single-cell atlas to enable in-depth characterization and rational engineering of CAR-T products
Sergio Camara-Peña, Paula Rodríguez-Márquez, Núria Planell…·Mikel Hernáez
The paper constructs a CAR-T cell functional atlas from over one million cells across 13 studies to link product composition with clinical response and identify sex- and age-dependent effects.