PathologybioRxivPreprint
H&E-stained Whole Slide Image Deep Learning Predicts SPOP Mutation State in Prostate Cancer
Andrew J. Schaumberg, Mark A. Rubin, Thomas J. Fuchs
This paper develops a deep learning model that predicts SPOP mutation status in prostate cancer from H&E-stained whole slide images, achieving high accuracy across different slide types and demonstrating content-based image retrieval for genetic-histologic relationships.