Xuhong Zhang

SpaGene improves spatial transcriptomics by imputing missing gene expressions, achieving higher accuracy than existing methods and revealing immune dynamics in lung tumors.

xSiGra is a graph-based AI model that identifies interpretable features in spatial single-cell data, showing that cell activity is influenced by neighboring cells and revealing endothelial-tumor interactions.

AMON identifies the origin of metabolites as host, microbial, or environmental to improve integration of microbiome and metabolome data.