Author

Frédéric G. Buono

Boehringer Ingelheim (United States)ORCID 0000-0001-7585-0438Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Hao Wu· 1 shared James HeuschkeliD· 1 shared Jeff Song· 1 shared Laura J. KingsleyiD· 1 shared Nathaniel BlalockiD· 1 shared Noah B. PefauriD· 1 shared Philip A. RomeroiD· 1 shared Ruihao Li· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Hao Wu

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintSep 17, 2026

Integrating complementary biological information for multi-objective enzyme engineering

Nathaniel Blalock, Yvett Sosa, James Heuschkel…·Philip A. Romero

This study develops a machine learning framework to engineer enzymes by integrating sparse data with evolutionary and structural information, achieving improvements in catalytic performance, yield, and stability.

DOI 10.64898/2026.09.15.751856

machine learning (classical)drug response / drug discovery

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