Author

Richard K. Assoian

University of PennsylvaniaORCID 0000-0001-7635-6204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Elizabeth A. HawthorneiD· 1 shared Ian RobertsiD· 1 shared Kyle BruuniD· 1 shared Paola A. CastagninoiD· 1 shared Ryan A. von KleeckiD· 1 shared Sonja A. BrankoviciD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Elizabeth A. HawthorneORCID

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1 paper

Recent·Most cited

Premature arterial stiffening in Hutchinson-Gilford Progeria Syndrome linked to early induction of Lysyl Oxidase (LOX) and corrected by LOX inhibition

Ryan A. von Kleeck, Sonja A. Brankovic, Ian Roberts, Elizabeth A. Hawthorne, Kyle Bruun, Paola A. Castagnino, Richard K. Assoian

This study identifies LOX upregulation as a key driver of premature arterial stiffening in HGPS and shows that LOX inhibition can restore normal arterial mechanics.

bioRxiv · Oct 4, 2019 · PreprintMolecular Biology