Author

Elizabeth A. Hawthorne

University of PennsylvaniaORCID 0000-0002-2740-9418Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ian RobertsiD· 1 shared Kyle BruuniD· 1 shared Paola A. CastagninoiD· 1 shared Richard K. AssoianiD· 1 shared Ryan A. von KleeckiD· 1 shared Sonja A. BrankoviciD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Ian RobertsORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintOct 4, 2019

Premature arterial stiffening in Hutchinson-Gilford Progeria Syndrome linked to early induction of Lysyl Oxidase (LOX) and corrected by LOX inhibition

Ryan A. von Kleeck, Sonja A. Brankovic, Ian Roberts…·Richard K. Assoian

This study identifies LOX upregulation as a key driver of premature arterial stiffening in HGPS and shows that LOX inhibition can restore normal arterial mechanics.

DOI 10.1101/773184

mousestatistical model

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