Author

Kate L. Del Bel

University of British ColumbiaORCID 0000-0001-7669-9530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Ashish SharmaiD· 2 shared Henry Y. LuiD· 2 shared Joshua DalmanniD· 2 shared Maggie P. FuiD· 2 shared Mehul SharmaiD· 2 shared Stuart E. TurveyiD· 2 shared Susan Xiaoqin LiniD· 2 shared Wyeth W. WassermaniD· 2 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Ashish SharmaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Human Germline Heterozygous Gain-of-Function STAT6 Variants Cause Severe Allergic Disease

Mehul Sharma, Daniel Leung, Mana Momenilandi, Lauren C.W. Jones, Lucia Pacillo, Alyssa E. James, Jill R. Murrell, Selket Delafontaine, Jesmeen Maimaris, Maryam Vaseghi‐Shanjani, Kate L. Del Bel, Henry Y. Lu, Gilbert T. Chua, Silvia Di Cesare, Oriol Fornés, , Stuart E. Turvey

This study identifies heterozygous gain-of-function STAT6 variants in two patients with severe allergic disease and shows JAK inhibitors reduce the enhanced STAT6 responses.

The Journal of Experimental Medicine · Feb 10, 2023Peer-reviewedGenetic & Genomic Medicine

Human germline biallelic complete NFAT1 deficiency causes the triad of progressive joint contractures, osteochondromas, and susceptibility to B cell malignancy

Mehul Sharma, Maggie P. Fu, Henry Y. Lu, Ashish Sharma, Bhavi P. Modi, Christina Michalski, Susan Xiaoqin Lin, Joshua Dalmann, Areesha Salman, Kate L. Del Bel, Meriam A. Waqas, Jefferson Terry, Audi Setiadi, Pascal M. Lavoie, Wyeth W. Wasserman, , Stuart E. Turvey

The paper identifies a human with complete NFAT1 deficiency, revealing its role in joint contractures, osteochondromas, and B cell malignancy through single-cell omic analyses.

Blood · Jul 5, 2022Peer-reviewedGenetic & Genomic Medicine