Effect of bedrest on the human gut and oral microbiome: implications for frailty
Monica Alvaro-Fuss, Vanessa DeClercq, Joanna M. Blodgett, Olga Theou, Morgan G. I. Langille, Robert Gerald Beiko
This study examines how bedrest affects gut and oral microbiomes in older adults, finding that inactivity reduces gut diversity and increases Bacteroides, while exercise mitigates these changes, and oral microbiome diversity is more strongly linked to frailty.
Experimental Gerontology · Feb 25, 2026Peer-reviewedMicrobiology