Alberto Meseguer

ModCRE-NN predicts transcription factor DNA-binding motifs by integrating structural and evolutionary data, showing improved performance under low similarity and uncertainty.

ModCRElib is a package for modeling cis-regulatory elements, offering tools for TF-DNA interaction analysis, binding motif prediction, and regulatory complex modeling.

The paper develops a computational method to predict DNA-binding preferences of C2H2-ZF domains using structural models and applies it to predict CTCF's binding sites.