Nicholas Matigian

This study uses spatial transcriptomics to identify placental dysfunction signatures in SARS-CoV-2 infected pregnancies, revealing altered gene expression related to hypoxia, oxidative stress, and preeclampsia-like pathways.

This study shows that host genetics significantly influences murine skin microbiota composition during homeostasis and wound healing, with genetic background explaining most variation in microbiota and healing speed.

MINT identifies reproducible molecular signatures across experiments by integrating data and accounting for systematic variation in a single step, improving classification accuracy.

This paper identifies a 16-gene molecular signature that accurately classifies mesenchymal stromal cells across sources and conditions.