Molecular arms race in WHO elements, a category of homing genetic elements distinct from inteins and introns
Matthieu Osborne, Ludovic Monnin, Kenneth H. Wolfe
The paper identifies an evolutionary arms race between WHO endonucleases and their target site in the FBA1 gene in Torulaspora yeast, showing rapid sequence diversification to evade cleavage.
bioRxiv · Aug 18, 2026 · PreprintEvolutionary Biology