Cancer Biologynpj Precision OncologyPeer-reviewed
Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers
Soufyan Lakbir, Renske de Wit, Ino de Bruijn…·Sanne Abeln
This study introduces tumor break load (TBL) as a measure of genomic instability across cancers, showing its association with gene expression changes and clinical outcomes.
6 citations