GeneticsProceedings of the National Academy of SciencesPeer-reviewed
Mendelian Randomization for causal inference accounting for pleiotropy and sample structure using genome-wide summary statistics
Xianghong Hu, Jia Zhao, Zhixiang Lin…·Can Yang
This paper introduces MR-APSS, a Mendelian Randomization method that addresses pleiotropy and sample structure to improve causal inference from GWAS summary statistics.
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