Xiang Wan

This paper introduces IBSEP, a statistical framework that integrates bulk and scRNA-seq data to prioritize cell-type-specific eQTLs, showing improved performance over existing methods.

BioOS provides a cloud-native platform for reproducible biomedical research by integrating data, code, tools, and environments into workspaces, enhancing data integrity and accessibility.

SpatialScope integrates spatial and single-cell transcriptomics data using deep generative models to achieve single-cell resolution and infer transcriptome-wide expression levels.

This paper introduces MR-APSS, a Mendelian Randomization method that addresses pleiotropy and sample structure to improve causal inference from GWAS summary statistics.

This paper introduces LOG-TRAM, a method to improve trans-ancestry association mapping by leveraging local genetic structure, enhancing power and reducing bias in under-represented populations.

FIRM integrates heterogeneous scRNA-seq datasets across tissues and platforms, accurately preserving cell type identities and structure.

This study quantifies 4D nuclear morphology changes in human astrocytes treated with valproic acid, showing significant size and shape differences by day 7.