Aaron Wing Cheung Kwok

DenoIST improves spatial transcriptomics data by removing contaminating transcripts, enhancing gene expression specificity and cell type annotation.

This paper reviews challenges in analyzing scATAC-seq data and argues that true single-cell chromatin accessibility profiling has not yet been achieved.

MQuad identifies clonally informative mitochondrial variants from single-cell sequencing data with high sensitivity and specificity, outperforming existing methods.