Kyoshiro Hiki

Statistical Causal Discovery in Developing and Refining Adverse Outcome Pathway (AOP)

This paper applies statistical causal discovery to ecotoxicology data to improve adverse outcome pathway models by identifying causal relationships and handling missing data.

Comprehensive Sequencing of Environmental RNA from Japanese Medaka at Various Size Fractions and Comparison with Skin RNA

The paper analyzes environmental RNA from Japanese medaka at different size fractions and compares it with skin RNA to determine optimal filtration methods and sources of eRNA.

Environmental RNA as a non-invasive tool for assessing toxic effects in fish: a proof-of-concept study using Japanese medaka exposed to pyrene

This study demonstrates that environmental RNA (eRNA) can detect gene expression changes in Japanese medaka fish exposed to pyrene, though it is largely bacterial and degraded.