Systems BiologybioRxivPreprint
Identifying potential biomarkers of response to CCR5Δ32 HSCT in HIV infection
Jason Chang, Feilim Mac Gabhann
Simulations using a mechanistic HIV model show that interindividual variability in infection dynamics drives differential responses to HSCT, with remission dependent on donor-to-host immune cell ratios and better predicted by clinical observations than model parameters.
DOI 10.1101/2025.03.30.646188