Synthetic BiologybioRxivPreprint
LM-GVP: A Generalizable Deep Learning Framework for Protein Property Prediction from Sequence and Structure
Zichen Wang, Steven A. Combs, Ryan M. Brand…·Peter Clark
This study introduces LM-GVP, a deep learning framework combining a protein Language Model and Graph Neural Network to predict protein properties from sequence and structure, outperforming existing methods on fluorescence, protease stability, and Gene Ontology function prediction.