Author

Anwaar Saeed

University of PittsburghORCID 0000-0001-8024-9401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Binfeng LuiD· 2 shared Xinghua LuiD· 2 shared Ahmed Omar KasebiD· 1 shared Alessandro ParisiiD· 1 shared Andrea DalbeniiD· 1 shared Antonio D’AlessioiD· 1 shared Aodong Qiu· 1 shared Aria TorkpouriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Binfeng LuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clinical and molecular characterisation of primary refractoriness to atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma.

Pasquale Lombardi, Erik Ramon‐Gil, Leonardo Brunetti, Giulia Francesca Manfredi, George Merces, Claudia Angela Maria Fulgenzi, Antonio D’Alessio, Aria Torkpour, Ciro Celsa, Bernardo Stefanini, Hannah Yang, Fionnuala Crowley, Thomas Urban Marron, Anwaar Saeed, Matthias Pinter, , David James Pinato

This study identifies clinical and molecular features of primary refractoriness to atezolizumab plus bevacizumab in HCC, showing poor outcomes and an immunosuppressive tumor microenvironment.

bioRxiv · Jul 8, 2025 · PreprintCancer Biology

Deconvoluting single-cell transcriptomics reveals cellular programs regulated by cell-cell communication in colorectal cancer

Han Zhang, Binfeng Lu, Aodong Qiu, Gregory F. Cooper, Anwaar Saeed, John William Paisley, Xinghua Lu, Lujia Chen

The paper uses single-cell data to identify gene expression modules regulated by cell-cell communication in colorectal cancer and validates findings with spatial transcriptomics.

bioRxiv · Apr 9, 2025 · PreprintBioinformatics

Current transcriptome database and biomarker discovery for immunotherapy by immune checkpoint blockade

Han Zhang, Binfeng Lu, Xinghua Lu, Anwaar Saeed, Lujia Chen

This paper reviews biomarkers for immune checkpoint blockade therapy, compares existing databases, and introduces IOhub, a web portal for benchmarking biomarkers using bulk and single-cell transcriptome datasets.

bioRxiv · Dec 9, 2024 · PreprintBioinformatics