Author

Jayant Kumar Singh

Indian Institute of Technology KanpurORCID 0000-0001-8056-2115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Approach:statistical model· 1

Frequent Co-Authors

Malay Ranjan BiswaliD· 2 shared Sudip Kumar RoyiD· 1 shared Sudip RoyiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 2 mutual co-author links

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2 shared papersBiophysics

Malay Ranjan BiswalORCID

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2 papers

Recent·Most cited

Comparative Analysis of Lipid Nanoparticles in Pfizer-BioNTech and Moderna COVID-19 Vaccines: Insights from Molecular Dynamics Simulations

Malay Ranjan Biswal, Sudip Kumar Roy, Jayant Kumar Singh

This study compares lipid nanoparticles in Pfizer-BioNTech and Moderna COVID-19 vaccines using molecular dynamics simulations, finding differences in ionizable lipid structure that may explain storage temperature differences.

bioRxiv · Oct 4, 2024 · PreprintBiophysics

In Silico Engineering of Stable siRNA Lipid Nanoparticles: Exploring the Impact of Ionizable Lipid Concentrations for Enhanced Formulation Stability

Malay Ranjan Biswal, Sudip Roy, Jayant Kumar Singh

This study uses molecular dynamics simulations to show that LNPs with positive ionizable lipids encapsulate more siRNA and require less force for siRNA escape compared to neutral lipids.

bioRxiv · Sep 25, 2024 · PreprintBiophysics