Type I PRMTs Play a Role in Mammalian Embryonic Lineage Specification
Jinlong Qiu, Yutong Chen, Pedro Beltrán-Álvarez, Roger G. Sturmey
This study shows that Type I PRMT-mediated ADMA is essential for lineage specification in mammalian embryos, disrupting Hippo signaling and cell allocation when inhibited.
bioRxiv · Aug 21, 2026 · PreprintDevelopmental Biology